Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 19/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037933 | 0.94 | CCKBR (0.68) | CCKBRKCNH2TP53 | |
| SCHEMBL9040464 | 0.85 | CCKBR (0.67) | CCKBRKCNH2 | |
| SCHEMBL9039706 | 0.84 | CCKBR (0.56) | CCKBRKCNH2 | |
| SCHEMBL9039394 | 0.83 | CCKBR (0.66) | CCKBRKCNH2 | |
| SCHEMBL9039642 | 0.83 | CCKBR (0.68) | CCKBR | |
| SCHEMBL9865274 | 0.82 | CCKBR (0.88) | CCKBRKCNH2 | |
| SCHEMBL9038983 | 0.81 | CCKBR (0.64) | CCKBR | |
| SCHEMBL9041762 | 0.81 | CYP3A4 (0.58) | CCKBR | |
| SCHEMBL9038361 | 0.80 | CCKBR (0.67) | CCKBRKCNH2 | |
| SCHEMBL9038055 | 0.80 | CCKBR (0.71) | CCKBRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004741-A | Cholecystokinin(CCK); Treating Disorders Of The Gastrointestinal Tract, Central Nervous System And Of The Appetite Of Animals | MERCK & CO., INC. (US) | 1991-04-02 | — | — | US | disclosed |