SCHEMBL9873195

SCHEMBL9873195

O=C(O)CCCCN1CCC(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)CC1

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP2J2 P51589 8/20 0.55
HRH1 P35367 4/20 0.54
KCNH2 Q12809 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9873524 0.96 CYP2J2 (0.58) CYP2J2HRH1KCNH2
Hydrochloric Acid SCHEMBL9873619 0.94 CYP2J2 (0.56) CYP2J2HRH1KCNH2
Hydrochloric Acid SCHEMBL9873629 0.94 CYP2J2 (0.56) CYP2J2HRH1KCNH2
SCHEMBL9873774 0.86 CYP2J2 (0.56) CYP2J2HRH1KCNH2
SCHEMBL9874017 0.86 CYP2J2 (0.51) CYP2J2HRH1KCNH2
SCHEMBL9872366 0.86 CYP2J2 (0.51) CYP2J2HRH1KCNH2
SCHEMBL9873499 0.85 CYP2J2 (0.50) CYP2J2HRH1KCNH2
SCHEMBL11864493 0.85 CYP2J2 (0.74) CYP2J2HRH1KCNH2
SCHEMBL9872538 0.84 CYP2J2 (0.58) CYP2J2HRH1KCNH2
SCHEMBL9871858 0.84 CYP2J2 (0.58) CYP2J2HRH1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5057524-A Asthma, dermatitis A. H. ROBINS COMPANY INCORPORATED (US) 1991-10-15 US claimed
US-5057524-A Asthma, dermatitis A. H. ROBINS COMPANY INCORPORATED (US) 1991-10-15 US disclosed