Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2J2 | P51589 | 12/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873355 | 0.94 | CYP2J2 (0.48) | CYP2J2KCNH2HRH1 | |
| SCHEMBL9873524 | 0.90 | CYP2J2 (0.58) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 | |
| Hydrochloric Acid SCHEMBL9873629 | 0.88 | CYP2J2 (0.56) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 | |
| Hydrochloric Acid SCHEMBL9873619 | 0.88 | CYP2J2 (0.56) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 | |
| SCHEMBL7321605 | 0.88 | CYP2J2 (0.72) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 | |
| SCHEMBL9873195 | 0.86 | CYP2J2 (0.55) | CYP2J2KCNH2HRH1 | |
| SCHEMBL9874649 | 0.85 | CYP2J2 (0.54) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 | |
| SCHEMBL9874468 | 0.85 | CYP2J2 (0.54) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 | |
| SCHEMBL9871849 | 0.85 | NPSR1 (0.51) | CYP2J2CYP3A4CYP2C9KCNH2MEN1 | |
| Oxalic Acid SCHEMBL11507687 | 0.84 | CYP2J2 (0.71) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |