Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 9/20 | 0.64 |
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.42 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.42 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30729937 | 0.94 | SYK (0.64) | SYKKMOSLC6A4EGFRERBB2 | |
| SCHEMBL21835202 | 0.94 | SYK (0.64) | SYKKMOSLC6A4EGFRERBB2 | |
| SCHEMBL8306570 | 0.84 | SYK (0.54) | SYKABCB1HTR1ADRD2AURKB | |
| SCHEMBL21835286 | 0.81 | SYK (0.50) | SYKEGFRERBB2ABCB1HTR1A | |
| SCHEMBL31442635 | 0.80 | MGAM (0.47) | SMN1; SMN2RAB9A | |
| SCHEMBL810931 | 0.80 | MGAM (0.47) | SMN1; SMN2RAB9A | |
| SCHEMBL29638125 | 0.78 | SYK (0.78) | SYKKMOSLC6A4EGFRERBB2 | |
| SCHEMBL30623239 | 0.78 | SYK (1.00) | SYKKMOSLC6A4EGFRERBB2 | |
| SCHEMBL159323 | 0.78 | SYK (0.78) | SYKKMOSLC6A4EGFRERBB2 | |
| SCHEMBL17601189 | 0.78 | SYK (1.00) | SYKKMOSLC6A4EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304572-A | 3-cyanoquinoline compound as well as pharmaceutical composition and application thereof | SHANGHAI PHARMACEUTICAL GROUP CO LTD | 2013-09-18 | — | — | CN | disclosed |
| US-5017213-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0351641-A1 | 1-Phenylpyrrole | NIHON BAYER AGROCHEM K.K. (JP) | 1990-01-24 | — | — | EP | disclosed |
| EP-0337151-A2 | N-substituted phenyl-heterocyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-10-18 | — | — | EP | disclosed |