Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872204 | 0.94 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9873358 | 0.93 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9875077 | 0.91 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9872990 | 0.89 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9873526 | 0.89 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9873343 | 0.89 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9872962 | 0.88 | AGTR1 (0.33) | AGTR1AGTR2 | |
| SCHEMBL9873851 | 0.88 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9874518 | 0.88 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9871494 | 0.87 | PDE10A (0.36) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019715-A1 | 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-26 | — | — | WO | disclosed |