SCHEMBL9873309

SCHEMBL9873309

CCOCCOC(=S)SC

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TSHR P16473 1/20 0.46
THRB P10828 1/20 0.41
CYP2D6 P10635 1/20 0.32
CA12 O43570 3/20 0.32
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CA9 Q16790 3/20 0.32
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17300579 0.88 CA12 (0.38) ALDH1A1TSHRCA12CA1CA2
SCHEMBL3369822 0.87 ALDH1A1 (0.36) ALDH1A1TSHRTHRBCYP2D6CA12
SCHEMBL25530954 0.85 ALDH1A1 (0.30) ALDH1A1CYP2D6
SCHEMBL17776428 0.84 CA12 (0.33) ALDH1A1TSHRTHRBCA12CA1
SCHEMBL18407217 0.84 CA12 (0.33) ALDH1A1TSHRTHRBCA12CA1
SCHEMBL9870408 0.80 ALDH1A1 (0.45) ALDH1A1TSHRTHRBCYP2D6CA12
SCHEMBL7434676 0.78
SCHEMBL411100 0.78
SCHEMBL9870541 0.77 ALDH1A1 (0.42) ALDH1A1TSHRTHRBCYP2D6
SCHEMBL6580504 0.75 ALDH1A1 (0.54) ALDH1A1TSHRTHRBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5026492-A Synergistic; improved wear resistance in internal combustion engines EXXON RESEARCH & ENGINEERING COMPANY (US) 1991-06-25 US disclosed