Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.48 |
| ▸ | PRCP | P42785 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873405 | 0.93 | CYP2J2 (0.54) | NPSR1HTTMEN1KMT2ACYP2D6 | |
| SCHEMBL9874087 | 0.92 | CYP2J2 (0.51) | NPSR1HTTMEN1KMT2ACYP2D6 | |
| SCHEMBL9875059 | 0.89 | CYP2J2 (0.58) | NPSR1HTTMEN1KMT2ACYP2D6 | |
| SCHEMBL9873976 | 0.88 | CYP2J2 (0.48) | NPSR1HTTALDH1A1CYP2J2RECQL | |
| SCHEMBL9874299 | 0.88 | HTT (0.60) | NPSR1HTTCYP2C9CYP2J2RECQL | |
| SCHEMBL9872613 | 0.86 | CYP2J2 (0.61) | L3MBTL1MEN1KMT2AALDH1A1CYP2J2 | |
| SCHEMBL9871242 | 0.85 | MEN1 (0.53) | NPSR1HTTMEN1KMT2ACYP2D6 | |
| SCHEMBL9873058 | 0.82 | CYP2J2 (0.65) | NPSR1HTTCYP2C9CYP2J2RECQL | |
| SCHEMBL9874649 | 0.81 | CYP2J2 (0.54) | MEN1KMT2ACYP2C9CYP2J2 | |
| SCHEMBL9873919 | 0.81 | CYP2J2 (0.61) | NPSR1HTTCYP2C9CYP2J2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |