Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873149 | 0.94 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9873520 | 0.92 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9873125 | 0.88 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9873633 | 0.88 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9872941 | 0.87 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9871433 | 0.87 | PDE4A (0.40) | AGTR1AGTR2 | |
| SCHEMBL9873785 | 0.86 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9873094 | 0.86 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9873196 | 0.85 | PDE7A (0.40) | — | |
| SCHEMBL9402500 | 0.84 | AGTR1 (0.57) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019715-A1 | 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-26 | — | — | WO | disclosed |