Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 16/20 | 0.60 |
| ▸ | TOP2A | P11388 | 2/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874575 | 0.83 | GSK3B (0.54) | GSK3BTOP2ATOP2BKDM4EKMT2A | |
| SCHEMBL9872970 | 0.81 | GSK3B (0.60) | GSK3BTOP2ATOP2BKDM4EKMT2A | |
| SCHEMBL9874833 | 0.81 | TOP2A (0.56) | GSK3BTOP2ATOP2BKDM4EKMT2A | |
| SCHEMBL9873482 | 0.79 | GSK3B (0.52) | GSK3BTOP2ATOP2BKDM4EKMT2A | |
| SCHEMBL1345178 | 0.79 | GSK3B (0.51) | GSK3BTOP2ATOP2B | |
| SCHEMBL10550876 | 0.75 | GSK3B (0.63) | GSK3BTOP2ATOP2BKMT2A | |
| SCHEMBL12160557 | 0.75 | GSK3B (1.00) | GSK3B | |
| SCHEMBL8231409 | 0.75 | GSK3B (1.00) | GSK3B | |
| SCHEMBL12130865 | 0.75 | GSK3B (1.00) | GSK3B | |
| SCHEMBL15101026 | 0.72 | GSK3B (0.74) | GSK3BTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |