Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788216 | 1.00 | MCL1 (0.50) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL7663205 | 1.00 | MCL1 (0.50) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL3951201 | 0.77 | MCL1 (0.60) | MCL1FBP1ALDH1A1TSHRPLIN1 | |
| SCHEMBL7572848 | 0.77 | MCL1 (0.46) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL3366325 | 0.77 | MCL1 (0.60) | MCL1FBP1ALDH1A1TSHRPLIN1 | |
| SCHEMBL7656907 | 0.77 | MCL1 (0.70) | MCL1FBP1ALDH1A1AKR1C3AKR1C1 | |
| SCHEMBL7660280 | 0.77 | MCL1 (0.46) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL4788817 | 0.76 | ALDH1A1 (0.46) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL197670 | 0.76 | ALDH1A1 (0.46) | MCL1FBP1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL7625514 | 0.74 | MCL1 (0.43) | MCL1FBP1ALDH1A1TSHRAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981847-A | Tricyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-01 | — | — | US | claimed |