Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 2/20 | 0.46 |
| ▸ | FNTB | P49356 | 2/20 | 0.46 |
| ▸ | SQLE | Q14534 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874540 | 1.00 | KMT2A (0.61) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL9874537 | 1.00 | KMT2A (0.61) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11072220 | 1.00 | KMT2A (0.61) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL9872878 | 1.00 | KMT2A (0.61) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL9873705 | 1.00 | KMT2A (0.61) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11072225 | 1.00 | KMT2A (0.61) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL9872875 | 1.00 | KMT2A (0.61) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL2725711 | 0.98 | KMT2A (0.59) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL2010822 | 0.98 | KMT2A (0.59) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL10577114 | 0.86 | PPARG (0.51) | KMT2AMAPTMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435423-A | Anti-ulcer composition comprising terpenoid containing two functional groups and method of treating ulcers | EISAI CO., LTD. (JP) | 1984-03-06 | — | — | US | claimed |
| US-4338251-A | Two-functional-group-containing terpenoids, processes for the preparation of the same, and anti-ulcer agents containing the same | EISAI CO., LTD. (JP) | 1982-07-06 | — | — | US | claimed |
| US-4992469-A | Prevention of cardiovascular disorder; phospholipase inhibitor | EISAI CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0163317-B1 | QUINONE DERIVATIVES, METHOD AND USE OF PREPARING SAME, AND PHARMACEUTICAL COMPOSITION | Eisai Co., Ltd. (JP) | 1988-08-24 | — | — | EP | disclosed |
| EP-0163317-A1 | Quinone derivatives, method and use of preparing same, and pharmaceutical composition | Eisai Co., Ltd. (JP) | 1985-12-04 | — | — | EP | disclosed |
| US-4468458-A | Two-functional-group-containing terpenoids, processes for the preparation of the same, and anti-ulcer agents containing the same | EISAI CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454330-A | Two-functional-group-containing terpenoids, processes for the preparation of the same, and anti-ulcer agents containing the same | EISAI CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |
| US-4435423-A | Anti-ulcer composition comprising terpenoid containing two functional groups and method of treating ulcers | EISAI CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |
| US-4386227-A | DIOLS PRODUCED BY MICROBIOLOGICAL OXIDATION | EISAI CO., LTD. (JP) | 1983-05-31 | — | — | US | disclosed |
| US-4338251-A | Two-functional-group-containing terpenoids, processes for the preparation of the same, and anti-ulcer agents containing the same | EISAI CO., LTD. (JP) | 1982-07-06 | — | — | US | disclosed |