SCHEMBL2010822

SCHEMBL2010822

C/C(=C\CO)CC/C=C(\C)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.59
ALOX15 P16050 3/20 0.59
MEN1 O00255 2/20 0.59
CYP3A4 P08684 2/20 0.59
MAPT P10636 2/20 0.57
ALDH1A1 P00352 2/20 0.57
UGT1A1 P22309 1/20 0.57
PPARG P37231 1/20 0.48
BACE1 P56817 1/20 0.46
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
FNTA P49354 2/20 0.43
FNTB P49356 2/20 0.43
SQLE Q14534 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2725711 1.00 KMT2A (0.59) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL9874540 0.98 KMT2A (0.61) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL9872878 0.98 KMT2A (0.61) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL11072220 0.98 KMT2A (0.61) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL9873705 0.98 KMT2A (0.61) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL9872875 0.98 KMT2A (0.61) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL9873716 0.98 KMT2A (0.61) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL11072225 0.98 KMT2A (0.61) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL9874537 0.98 KMT2A (0.61) KMT2AALOX15MEN1CYP3A4MAPT
SCHEMBL2727334 0.85 KMT2A (0.61) KMT2AALOX15MEN1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4064150-A SELECTIVE GAMMA-ALKYLATION OF ALPHA,BETA-UNSATURATED ACIDS WITH ALLYLIC ELECTROPHILES, DICOPPER(I) DIENOLATES UNIVERSITY OF ILLINOIS FOUNDATION (US) 1977-12-20 US claimed
JP-56113718-A None JP disclosed
US-12215126-B2 Cationic steroidal antimicrobial compounds with endogenous groups BRIGHAM YOUNG UNIVERSITY (US) 2025-02-04 US disclosed
US-12042550-B2 Leave-on hair treatment compositions L'OREAL (FR) 2024-07-23 US disclosed
US-20240156699-A1 HAIR TREATMENT COMPOSITION L'OREAL (FR) 2024-05-16 US disclosed
WO-2024097630-A1 HAIR TREATMENT COMPOSITION L'OREAL (FR) 2024-05-10 WO disclosed
US-20240122821-A1 LEAVE-ON HAIR TREATMENT COMPOSITIONS L'OREAL (FR) 2024-04-18 US disclosed
US-20240122833-A1 METHOD FOR REMOVING COLOR FROM ARTIFICIALLY COLORED HAIR L'OREAL (FR) 2024-04-18 US disclosed
EP-4346747-A1 COSMETIC COMPOSITION COMPRISING VITAMIN C L'OREAL (FR) 2024-04-10 EP disclosed
WO-2024073637-A1 LEAVE-ON HAIR TREATMENT COMPOSITIONS L'OREAL (FR) 2024-04-04 WO disclosed
US-6303654-B1 EXPOSING TUMOR CELLS TO FARNESYL ANTHRANILATE AND CARRIER TO INHIBIT OR REDUCE TUMOR CELL GROWTH WISCONSIN ALUMNI RESEARCH FOUNDATION 2001-10-16 US disclosed
US-6207705-B1 FOR KILLING INSECTS, TICKS, NEMATODES, THEIR EGGS AND LARVE; VOLATALITY, FUMICATION, NONTOXIC IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2001-03-27 US disclosed
WO-2001008653-A1 SKIN CARE COMPOSITION UNILEVER PLC (GB) 2001-02-08 WO disclosed
EP-1061907-A1 MONOTERPENOID DERIVATIVES FOR TREATMENT OF CANCER WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2000-12-27 EP disclosed
WO-1999045912-A1 MONOTERPENOID DERIVATIVES FOR TREATMENT OF CANCER WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1999-09-16 WO disclosed
US-4992469-A Prevention of cardiovascular disorder; phospholipase inhibitor EISAI CO., LTD. (JP) 1991-02-12 US disclosed
EP-0163317-B1 QUINONE DERIVATIVES, METHOD AND USE OF PREPARING SAME, AND PHARMACEUTICAL COMPOSITION Eisai Co., Ltd. (JP) 1988-08-24 EP disclosed
EP-0163317-A1 Quinone derivatives, method and use of preparing same, and pharmaceutical composition Eisai Co., Ltd. (JP) 1985-12-04 EP disclosed
JP-S56113718-A BIFUNCTIONAL TERPENOID, ITS PREPARATION, AND ULCER PREVENTIVE AGENT COMPRISING IT AGENCY OF IND SCIENCE & TECHNOL 1981-09-07 JP disclosed
US-4064150-A SELECTIVE GAMMA-ALKYLATION OF ALPHA,BETA-UNSATURATED ACIDS WITH ALLYLIC ELECTROPHILES, DICOPPER(I) DIENOLATES UNIVERSITY OF ILLINOIS FOUNDATION (US) 1977-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12042550-B2 Leave-on hair treatment compositions ALG3, DEGS1, DSG1 KMT2A 3194/4885ALOX15 106/4885MEN1 538/4885
US-20240122821-A1 LEAVE-ON HAIR TREATMENT COMPOSITIONS ALG3, DEGS1, DSG1 KMT2A 3194/4885ALOX15 106/4885MEN1 538/4885
US-20240156699-A1 HAIR TREATMENT COMPOSITION DEGS1, POLR1C, PHOSPHO1 KMT2A 986/4885ALOX15 1770/4885MEN1 710/4885
US-12215126-B2 Cationic steroidal antimicrobial compounds with endogenous groups FPR3, NR3C2, HSD17B7 KMT2A 4660/4885ALOX15 312/4885MEN1 3278/4885
US-20240122833-A1 METHOD FOR REMOVING COLOR FROM ARTIFICIALLY COLORED HAIR TYR, COXFA4L2, CAT KMT2A 297/4885ALOX15 3382/4885MEN1 3963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.