Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357824 | 0.76 | POLB (0.37) | L3MBTL1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL3357819 | 0.76 | POLB (0.37) | L3MBTL1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL487130 | 0.76 | SRC (0.52) | SRCL3MBTL1TDP1KDM4EMEN1 | |
| Triphenyl Phosphate SCHEMBL10793117 | 0.72 | SRC (0.58) | SRCL3MBTL1TDP1KDM4ECYP2C9 | |
| SCHEMBL11098684 | 0.72 | SRC (0.58) | SRCL3MBTL1TDP1KDM4ECYP2C9 | |
| Triphenyl Phosphate SCHEMBL483692 | 0.71 | SRC (0.64) | SRCL3MBTL1TDP1KDM4ECYP2C9 | |
| Triphenyl Phosphate SCHEMBL18116 | 0.71 | SRC (0.64) | SRCL3MBTL1TDP1KDM4ECYP2C9 | |
| SCHEMBL28563480 | 0.71 | SRC (0.64) | SRCL3MBTL1TDP1KDM4ECYP2C9 | |
| Triphenyl Phosphate SCHEMBL28761613 | 0.71 | SRC (0.64) | SRCL3MBTL1TDP1KDM4ECYP2C9 | |
| Triphenyl Phosphate SCHEMBL28557783 | 0.71 | SRC (0.64) | SRCL3MBTL1TDP1KDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987136-A | OPIOID ANTAGONISTS | THE ROCKEFELLER UNIVERSITY (US) | 1991-01-22 | — | — | US | disclosed |
| EP-0103636-B1 | USE OF OPIUM ANTAGONISTS FOR THE MANUFACTURE OF MEDICAMENTS FOR CONTROLLING GASTROINTESTINAL DYSMOTILITY | ROCKEFELLER UNIVERSITY (US) | 1990-09-12 | — | — | EP | disclosed |
| EP-0103636-A4 | USE OF OPIUM ANTAGONISTS FOR THE MANUFACTURE OF MEDICAMENTS FOR CONTROLLING GASTROINTESTINAL DYSMOTILITY. | UNIV ROCKEFELLER (US) | 1986-03-04 | — | — | EP | disclosed |
| EP-0103636-A1 | USE OF OPIUM ANTAGONISTS FOR THE MANUFACTURE OF MEDICAMENTS FOR CONTROLLING GASTROINTESTINAL DYSMOTILITY. | UNIV ROCKEFELLER (US) | 1984-03-28 | — | — | EP | disclosed |
| WO-1983003197-A1 | METHOD FOR CONTROLLING GASTROINTESTINAL DYSMOTILITY | UNIV ROCKEFELLER (US) | 1983-09-29 | — | — | WO | disclosed |