Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815313 | 0.88 | TSHR (0.42) | TSHRALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL2001481 | 0.82 | TSHR (0.52) | TSHRALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL9873486 | 0.79 | TSHR (0.41) | TSHRALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL27213906 | 0.78 | CA12 (0.47) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL13341770 | 0.76 | TSHR (0.46) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL29009868 | 0.76 | CA1 (0.40) | CA1CA2 | |
| SCHEMBL2184188 | 0.76 | TSHR (0.48) | TSHRALDH1A1HPGDCA12CA1 | |
| SCHEMBL6648790 | 0.75 | KDM4E (0.40) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL1415209 | 0.75 | AGBL2 (0.42) | ALDH1A1SMN1; SMN2MAPTLMNANPSR1 | |
| SCHEMBL7008683 | 0.75 | TSHR (0.44) | TSHRALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |