Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28443915 | 0.82 | SLC6A4 (0.42) | ALDH1A1HPGDADRB2ADRB1ADRB3 | |
| SCHEMBL19003444 | 0.81 | ALDH1A1 (0.58) | ALDH1A1HPGDSLC6A2SLC6A3DPP4 | |
| SCHEMBL11228973 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HPGDADRB2ADRB1ADRB3 | |
| SCHEMBL23431370 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HPGDADRB2ADRB1ADRB3 | |
| SCHEMBL6204140 | 0.79 | NPC1 (0.57) | SMN1; SMN2NPC1LMNAKMT2AEPHX2 | |
| SCHEMBL21633354 | 0.78 | CYP1A2 (0.47) | ALDH1A1HPGDSLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL22040780 | 0.77 | GAA (0.43) | ALDH1A1HPGDADRB2ADRB1ADRB3 | |
| SCHEMBL22039703 | 0.77 | GAA (0.43) | ALDH1A1HPGDADRB2ADRB1ADRB3 | |
| SCHEMBL23878273 | 0.77 | GAA (0.43) | ALDH1A1HPGDADRB2ADRB1ADRB3 | |
| SCHEMBL13262327 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HPGDSLC6A2SLC6A3ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983606-A | Pharmaceutically-active phthalazine compounds | ZAMBON GROUP S.P.A. (IT) | 1991-01-08 | — | — | US | disclosed |