Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 6/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160932 | 0.93 | KDM4E (0.50) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9152404 | 0.90 | NPC1 (0.50) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9154082 | 0.90 | FFAR1 (0.48) | RAB9ASMN1; SMN2NPC1HSD17B10ACACB | |
| SCHEMBL9152764 | 0.87 | ACACB (0.50) | ACACBFFAR1CHRNB2CHRNA4 | |
| SCHEMBL9874333 | 0.83 | FFAR1 (0.39) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9766671 | 0.83 | RAB9A (0.50) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL10513163 | 0.82 | MCHR1 (0.45) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9855096 | 0.80 | NPC1 (0.46) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL10515249 | 0.79 | MCHR1 (0.42) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9855564 | 0.78 | HPGD (0.47) | KDM4EALDH1A1HPGDL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |