SCHEMBL987449

SCHEMBL987449

Nc1ccc(CC(=O)O)c(N)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.45
CYP2C19 P33261 3/20 0.45
CYP2C9 P11712 2/20 0.45
MAPT P10636 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
MEN1 O00255 2/20 0.44
THRB P10828 2/20 0.44
RECQL P46063 2/20 0.44
KMT2A Q03164 2/20 0.44
USP2 O75604 1/20 0.44
POLB P06746 1/20 0.44
PKM P14618 1/20 0.44
APEX1 P27695 1/20 0.44
BLM P54132 1/20 0.44
MCL1 Q07820 1/20 0.44
AKR1B1 P15121 2/20 0.42
SRC P12931 1/20 0.41
CYP1A2 P05177 1/20 0.40
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29393814 1.00 HPGD (0.45) HPGDCYP2C19CYP2C9MAPTTDP1
SCHEMBL10790156 0.98 HPGD (0.44) HPGDCYP2C19CYP2C9MAPTTDP1
SCHEMBL10790173 0.98 HPGD (0.44) HPGDCYP2C19CYP2C9MAPTTDP1
SCHEMBL14221079 0.85 HPGD (0.46) HPGDCYP2C19CYP2C9MAPTTDP1
SCHEMBL5159793 0.83 MAPT (0.39) HPGDCYP2C19CYP2C9MAPTTDP1
SCHEMBL115261 0.83 MAPT (0.48) HPGDCYP2C19CYP2C9MAPTTDP1
SCHEMBL2745778 0.83 MAPT (0.53) HPGDCYP2C19CYP2C9MAPTTDP1
SCHEMBL30692089 0.83 MAPT (0.48) HPGDCYP2C19CYP2C9MAPTTDP1
SCHEMBL10931514 0.82 CAMK2A (0.51) HPGDCYP2C9MEN1KMT2AAKR1B1
SCHEMBL16413297 0.82 GAA (0.52) HPGDMAPTTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103450068-B A kind of synthetic method of Ziprasidone intermediate CHONGQING CHANGJIE MEDICAL CHEMICAL CO., LTD. (CN) 2015-09-16 CN claimed
CN-103450068-A Synthetic method of ziprasidone intermediate CHONGQING CHANGJIE MEDICINE CHEMICAL CO LTD 2013-12-18 CN claimed
CN-1068621-C Polyimide compositions for electrodeposition and coatings formed of the same HIROSHI ITATANI (JP) 2001-07-18 CN claimed
EP-0770638-B1 Polyimide compositions for electrodeposition and coatings formed of the same ITATANI HIROSHI (JP) 1999-06-02 EP claimed
US-5741599-A Polyimide compositions for electrodeposition and coatings formed of the same PI MATERIALS RESEARCH LABORATORY (JP) 1998-04-21 US claimed
CN-1154988-A Polyimide compositions for electrodeposition and coatings formed of the same PI MATERIALS RESEARCH LAB (JP) 1997-07-23 CN claimed
EP-0770638-A1 Polyimide compositions for electrodeposition and coatings formed of the same PI MATERIAL RESEARCH LABORATORY (JP) 1997-05-02 EP claimed
EP-0161632-B1 PYRROLO-BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND INTERMEDIATES Roche Diagnostics GmbH (DE) 1991-04-10 EP claimed
US-4684371-A Oxidation hair dyes comprising m-phenylenediamine derivatives as coupling components HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1987-08-04 US claimed
CN-110824787-B Optical shutter for camera module and method for manufacturing the same 夏普株式会社 2023-04-11 CN disclosed
US-11569508-B2 Binder resin for lithium secondary battery electrode, electrode for lithium secondary battery, and lithium secondary battery PI R&D CO., LTD. (JP) 2023-01-31 US disclosed
CN-114437522-A High-temperature-resistant PET-PI composite film and adhesive tape thereof 苏州世华新材料科技股份有限公司 2022-05-06 CN disclosed
CN-110068959-B Liquid crystal display device and method for manufacturing liquid crystal display device 夏普株式会社 2022-03-04 CN disclosed
CN-110750015-B Liquid crystal display device having a plurality of pixel electrodes 夏普株式会社 2022-01-07 CN disclosed
EP-0161632-A2 Pyrrolo-benzimidazoles, process for their preparation, medicaments containing them and intermediates Roche Diagnostics GmbH (DE) 1985-11-21 EP disclosed
EP-0049338-B1 INK FOR USE IN INK JET PRINTING International Business Machines Corporation (US) 1984-11-21 EP disclosed
EP-0039455-B1 COUPLING COMPONENTS FOR OXIDATION HAIR DYES, THEIR PRODUCTION AND HAIR DYEING COMPOSITION CONTAINING THESE Henkel Kommanditgesellschaft auf Aktien (DE) 1984-07-04 EP disclosed
EP-0049338-A1 Ink for use in ink jet printing International Business Machines Corporation (US) 1982-04-14 EP disclosed
EP-0039455-A1 Coupling components for oxidation hair dyes, their production and hair dyeing composition containing these Henkel Kommanditgesellschaft auf Aktien (DE) 1981-11-11 EP disclosed
US-4286989-A Formulations for ink jet printing INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1981-09-01 US disclosed