SCHEMBL115261

SCHEMBL115261

Nc1ccc(N)c(CC(=O)O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.48
THRB P10828 3/20 0.48
RECQL P46063 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
USP2 O75604 1/20 0.48
POLB P06746 1/20 0.48
PKM P14618 1/20 0.48
APEX1 P27695 1/20 0.48
BLM P54132 1/20 0.48
MCL1 Q07820 1/20 0.48
HPGD P15428 4/20 0.45
CYP2C19 P33261 3/20 0.45
CYP2C9 P11712 2/20 0.45
AKR1B1 P15121 2/20 0.42
SRC P12931 1/20 0.41
CYP1A2 P05177 1/20 0.40
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30692089 1.00 MAPT (0.48) MAPTTHRBRECQLTDP1KMT2A
SCHEMBL14221079 0.85 HPGD (0.46) MAPTTHRBRECQLTDP1KMT2A
SCHEMBL987449 0.83 HPGD (0.45) MAPTTHRBRECQLTDP1KMT2A
SCHEMBL9021045 0.83 THRB (0.44) MAPTTHRBRECQLTDP1KMT2A
SCHEMBL29393814 0.83 HPGD (0.45) MAPTTHRBRECQLTDP1KMT2A
SCHEMBL6030152 0.82 AKR1B1 (0.55) MAPTTHRBRECQLTDP1KMT2A
SCHEMBL10790156 0.82 HPGD (0.44) MAPTTHRBRECQLTDP1KMT2A
SCHEMBL29221773 0.82 EGFR (0.49) KMT2AMEN1POLBHPGDCYP2C9
SCHEMBL10790173 0.82 HPGD (0.44) MAPTTHRBRECQLTDP1KMT2A
SCHEMBL16179546 0.82 GAA (0.52) MAPTTDP1KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117264151-A Covalent organic framework material capable of regulating and controlling effectiveness of acidic groups, and preparation method and application thereof 同济大学 2023-12-22 CN disclosed
US-20120057115-A1 LIQUID CRYSTAL DISPLAY DEVICE PANASONIC LIQUID CRYSTAL DISPLAY CO., LTD. 2012-03-08 US disclosed
US-4684371-A Oxidation hair dyes comprising m-phenylenediamine derivatives as coupling components HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1987-08-04 US disclosed
EP-0027284-B1 COPOLYMER LATEX AND PHOTOGRAPHIC SILVER HALIDE MATERIALS CONTAINING SUCH LATEX AGFA-GEVAERT N.V. (BE) 1983-09-14 EP disclosed
EP-0037602-A1 Photographic elements containing novel cyan-forming colour couplers AGFA-GEVAERT N.V. (BE) 1981-10-14 EP disclosed
EP-0027284-A1 Copolymer latex and photographic silver halide materials containing such latex AGFA-GEVAERT N.V. (BE) 1981-04-22 EP disclosed