Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TOP2A | P11388 | 7/20 | 0.66 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | ALB | P02768 | 1/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.66 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.65 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | TUBB | P07437 | 1/20 | 0.65 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.65 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.65 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.65 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.65 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.65 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.65 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10577413 | 0.95 | KDM4E (0.65) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL10578766 | 0.91 | KDM4E (0.62) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL2089512 | 0.87 | KDM4E (0.72) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL29406062 | 0.87 | KDM4E (0.72) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL2333806 | 0.87 | KDM4E (0.72) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL29872315 | 0.87 | KDM4E (0.72) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL2877827 | 0.87 | KDM4E (0.72) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL9872786 | 0.87 | KDM4E (0.64) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL9873615 | 0.86 | TOP2A (0.52) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| Bromide SCHEMBL9872550 | 0.86 | KDM4E (0.66) | KDM4EKMT2ATOP2ATOP2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |