Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.62 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.62 |
| ▸ | BRS3 | P32247 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874352 | 0.86 | AGTR1 (0.51) | AGTR1AGTR2BRS3PPARG | |
| SCHEMBL8392550 | 0.85 | AGTR1 (0.61) | AGTR1AGTR2PPARG | |
| SCHEMBL8392698 | 0.83 | AGTR1 (0.61) | AGTR1AGTR2PPARG | |
| SCHEMBL9874652 | 0.81 | AGTR1 (0.71) | AGTR1AGTR2PPARG | |
| SCHEMBL9873338 | 0.80 | AGTR1 (0.57) | AGTR1AGTR2BRS3PPARG | |
| SCHEMBL9872350 | 0.80 | AGTR1 (0.53) | AGTR1AGTR2BRS3PPARG | |
| SCHEMBL9874384 | 0.80 | AGTR1 (0.59) | AGTR1AGTR2BRS3PPARG | |
| SCHEMBL9871819 | 0.79 | AGTR1 (0.58) | AGTR1AGTR2BRS3PPARG | |
| SCHEMBL9872679 | 0.79 | AGTR1 (0.68) | AGTR1AGTR2PPARG | |
| SCHEMBL9873136 | 0.78 | AGTR1 (0.60) | AGTR1AGTR2BRS3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019715-A1 | 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-26 | — | — | WO | claimed |
| WO-1991019715-A1 | 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-26 | — | — | WO | disclosed |