Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446777 | 0.89 | GHSR (0.41) | GHSREPHX2DPP8DPP9DRD2 | |
| SCHEMBL16032520 | 0.75 | EPHX2 (0.41) | GHSREPHX2DPP8DPP9DRD2 | |
| SCHEMBL23223760 | 0.73 | GHSR (0.45) | GHSREPHX2DPP8DPP9DRD2 | |
| SCHEMBL18088760 | 0.73 | GHSR (0.45) | GHSREPHX2DPP8DPP9DRD2 | |
| SCHEMBL16350191 | 0.73 | GHSR (0.46) | GHSREPHX2DPP8DPP9DRD2 | |
| SCHEMBL2813574 | 0.72 | GHSR (0.63) | GHSREPHX2DRD2BACE1 | |
| SCHEMBL29715495 | 0.72 | GHSR (0.63) | GHSREPHX2DRD2BACE1 | |
| SCHEMBL18614234 | 0.72 | GHSR (0.63) | GHSREPHX2DRD2BACE1 | |
| SCHEMBL31232485 | 0.71 | SLC6A2 (0.46) | GHSREPHX2DPP8DPP9TAS1R3 | |
| SCHEMBL3375618 | 0.71 | PDE4A (0.52) | EPHX2DRD2TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041673-A | Aminopeptidase inhibitors, immunomodulators, analgesics | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-08-20 | — | — | US | disclosed |