Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554459 | 0.77 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL9801451 | 0.72 | TAAR1 (0.34) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL454620 | 0.71 | TAAR1 (0.39) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL10644320 | 0.70 | CHRM2 (0.36) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL28848601 | 0.67 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL73498 | 0.67 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL10536090 | 0.67 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL10422228 | 0.67 | SLC6A2 (0.35) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL13815321 | 0.66 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL11577478 | 0.64 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994480-A | Protecting plants, industrial materials | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-19 | — | — | US | disclosed |
| EP-0338344-A2 | Substituted triazolyl methyl carbinoles | BAYER AG (DE) | 1989-10-25 | — | — | EP | disclosed |