Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.45 |
| ▸ | CNR2 | P34972 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 2/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.35 |
| ▸ | TUBB | P07437 | 3/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872703 | 0.94 | CNR1 (0.45) | CNR1CNR2KDM4EKMT2ASTAT3 | |
| SCHEMBL9873617 | 0.92 | KDM4E (0.53) | CNR1CNR2KDM4EKMT2ASTAT3 | |
| SCHEMBL9874431 | 0.87 | CNR1 (0.39) | CNR1CNR2KDM4EKMT2ASTAT3 | |
| SCHEMBL9873589 | 0.84 | KDM4E (0.62) | CNR1CNR2KDM4EKMT2ATOP2A | |
| SCHEMBL9873439 | 0.83 | STAT3 (0.43) | CNR1CNR2KDM4EKMT2ASTAT3 | |
| SCHEMBL9873812 | 0.81 | KDM4E (0.62) | CNR1CNR2KDM4EKMT2ASTAT3 | |
| SCHEMBL1344388 | 0.79 | CNR1 (0.58) | CNR1CNR2KDM4EKMT2ASTAT3 | |
| SCHEMBL12130966 | 0.79 | CNR1 (0.58) | CNR1CNR2KDM4EKMT2ASTAT3 | |
| SCHEMBL25374200 | 0.73 | CNR2 (0.67) | CNR1CNR2KDM4EKMT2ASTAT3 | |
| SCHEMBL30542704 | 0.73 | CNR2 (0.67) | CNR1CNR2KDM4EKMT2ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |