Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.36 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.36 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GNRHR | P30968 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873617 | 0.84 | KDM4E (0.53) | STAT3KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL9874750 | 0.83 | CNR1 (0.45) | STAT3ADRB2KMT2AKDM4ECNR1 | |
| SCHEMBL9872703 | 0.83 | CNR1 (0.45) | STAT3TSHRMAPK1ADRB2KMT2A | |
| SCHEMBL10921287 | 0.79 | STAT3 (0.54) | STAT3PIM1IRAK1CAMK2BCAMK2G | |
| SCHEMBL9874431 | 0.77 | CNR1 (0.39) | STAT3ADRB2KMT2AKDM4EHPGD | |
| SCHEMBL9873589 | 0.76 | KDM4E (0.62) | KMT2AKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL9874569 | 0.74 | RORC (0.41) | TSHRMAPK1KMT2AHTTKDM4E | |
| SCHEMBL11073852 | 0.69 | STAT3 (0.41) | STAT3ADRB2KMT2AHTTKDM4E | |
| SCHEMBL9872260 | 0.69 | KDM4E (0.62) | KMT2AKDM4E | |
| SCHEMBL9873914 | 0.69 | GSK3B (0.38) | STAT3PIM1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |