Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.55 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.55 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.54 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.54 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.54 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.54 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.54 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.54 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.54 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.54 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.54 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.54 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.54 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.54 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.54 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.54 |
| ▸ | PSMA8 | Q8TAA3 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875351 | 0.90 | CNR1 (0.60) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL10666801 | 0.90 | CNR1 (0.60) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL9875930 | 0.90 | CNR1 (0.60) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL27761922 | 0.83 | SOAT1 (0.56) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL9412800 | 0.81 | SOAT2 (0.54) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL8856270 | 0.81 | SOAT2 (0.54) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL8856245 | 0.81 | SOAT2 (0.54) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL8856278 | 0.81 | SOAT2 (0.54) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL9857735 | 0.80 | CNR1 (0.55) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL8856131 | 0.80 | SOAT2 (0.53) | SOAT2SOAT1PSMB11PSMA7PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245687-B1 | SUBSTITUTED PYRIMIDINE AMIDES OF OLEIC OR LINOLEIC ACID AS INHIBITORS OF ACYL-COA CHOLESTEROL ACYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1991-02-27 | — | — | EP | claimed |
| US-4722927-A | ANTICHOLESTEROL AGENTS | WARNER-LAMBERT COMPANY (US) | 1988-02-02 | — | — | US | disclosed |