Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31399053 | 0.91 | DHODH (0.55) | DHODHALDH1A1HPGDHTTCYP19A1 | |
| SCHEMBL29254508 | 0.90 | DHODH (0.64) | DHODHALDH1A1NPSR1GAARAB9A | |
| SCHEMBL29254469 | 0.88 | DHODH (0.55) | DHODHALDH1A1HPGDHTTCYP19A1 | |
| SCHEMBL31399059 | 0.88 | DHODH (0.52) | DHODHALDH1A1HPGDHTTCYP19A1 | |
| SCHEMBL29254489 | 0.88 | DHODH (0.52) | DHODHALDH1A1HPGDHTTCYP19A1 | |
| SCHEMBL31399058 | 0.88 | DHODH (0.52) | DHODHALDH1A1HPGDHTTCYP19A1 | |
| SCHEMBL545096 | 0.87 | DHODH (0.75) | DHODHALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL9873320 | 0.86 | DHODH (0.59) | DHODHALDH1A1HPGDCYP19A1NPSR1 | |
| SCHEMBL7068076 | 0.86 | DHODH (0.65) | DHODHALDH1A1HPGDHTTCYP19A1 | |
| SCHEMBL3561102 | 0.85 | DHODH (0.54) | DHODHALDH1A1HPGDHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |