Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874613 | 0.94 | DHODH (0.63) | DHODHNPSR1CYP19A1MAPTGAA | |
| SCHEMBL29254508 | 0.91 | DHODH (0.64) | DHODHNPSR1MAPTGAATDP1 | |
| SCHEMBL10863680 | 0.87 | DHODH (0.77) | DHODHNPSR1MAPTGAATDP1 | |
| SCHEMBL13885851 | 0.86 | DHODH (0.58) | DHODHNPSR1MAPTGAATDP1 | |
| SCHEMBL9874767 | 0.86 | DHODH (0.58) | DHODHNPSR1CYP19A1MAPTGAA | |
| SCHEMBL3565253 | 0.86 | DHODH (0.58) | DHODHNPSR1MAPTGAATDP1 | |
| SCHEMBL3565256 | 0.86 | DHODH (0.58) | DHODHNPSR1MAPTGAATDP1 | |
| SCHEMBL11084961 | 0.85 | DHODH (0.67) | DHODHNPSR1MAPTGAATDP1 | |
| SCHEMBL29254476 | 0.82 | DHODH (0.57) | DHODHNPSR1MAPTGAATDP1 | |
| SCHEMBL10474341 | 0.82 | DHODH (0.57) | DHODHNPSR1MAPTGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |