Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 14/20 | 0.42 |
| ▸ | MELK | Q14680 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875116 | 0.88 | GAA (0.44) | GAAKDM4EMEN1KMT2ADYRK1A | |
| SCHEMBL9875111 | 0.84 | GAA (0.44) | GAAKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL9177795 | 0.79 | DYRK1A (0.45) | GAAKDM4EMEN1KMT2ADYRK1A | |
| SCHEMBL9315945 | 0.75 | MEN1 (0.48) | GAAKDM4EMEN1KMT2ADYRK1A | |
| SCHEMBL2280172 | 0.74 | KMT2A (0.54) | GAAKDM4EMEN1KMT2ADYRK1A | |
| SCHEMBL9872808 | 0.73 | KMT2A (0.40) | GAAKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL29810205 | 0.73 | DYRK1A (0.50) | GAAKDM4EMEN1KMT2ADYRK1A | |
| SCHEMBL29810202 | 0.73 | DYRK1A (0.50) | GAAKDM4EMEN1KMT2ADYRK1A | |
| SCHEMBL6286366 | 0.73 | DYRK1A (0.50) | GAAKDM4EMEN1KMT2ADYRK1A | |
| SCHEMBL23383058 | 0.73 | MAPT (0.37) | GAAKDM4EMEN1KMT2ADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |