Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874772 | 0.84 | GAA (0.44) | GAAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL9874344 | 0.76 | GAA (0.46) | GAAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL9874892 | 0.74 | GAA (0.53) | GAAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL9875116 | 0.72 | GAA (0.44) | GAAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL9382963 | 0.70 | KMT2A (0.64) | GAAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL10607926 | 0.70 | KDM4E (0.72) | GAAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL21982994 | 0.66 | LMNA (0.61) | GAAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL10678542 | 0.65 | KMT2A (0.67) | GAAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL10670596 | 0.65 | KDM4E (0.69) | GAAMEN1KMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL10676254 | 0.65 | MAPK1 (0.67) | GAAMEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |