Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875062 | 0.88 | KMT2A (0.46) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL2835973 | 0.83 | KDM4C (0.44) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL13544937 | 0.78 | KDM4E (0.41) | KMT2AMEN1HTTMAPTKDM4E | |
| SCHEMBL9875561 | 0.77 | MEN1 (0.61) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL9873291 | 0.75 | KMT2A (0.45) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL9872674 | 0.75 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL11007722 | 0.74 | MCL1 (0.47) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL9874603 | 0.74 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL28854487 | 0.73 | KMT2A (0.57) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL2839401 | 0.71 | MEN1 (0.51) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |