Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28553963 | 0.92 | CRHBP (0.57) | CRHBPCRHR2ESR1ESR2LMNA | |
| SCHEMBL27821076 | 0.92 | CRHBP (0.57) | CRHBPCRHR2ESR1ESR2LMNA | |
| SCHEMBL5402590 | 0.88 | CRHBP (0.54) | CRHBPCRHR2ESR1ESR2LMNA | |
| SCHEMBL10548703 | 0.88 | GAA (0.50) | CRHBPCRHR2LMNAKDM4EALDH1A1 | |
| SCHEMBL32684616 | 0.87 | CRHBP (0.56) | CRHBPCRHR2ESR1ESR2LMNA | |
| SCHEMBL10641894 | 0.87 | CRHBP (0.53) | CRHBPCRHR2ESR1ESR2LMNA | |
| SCHEMBL28104351 | 0.86 | CRHBP (0.49) | CRHBPCRHR2ESR1ESR2LMNA | |
| SCHEMBL10414886 | 0.85 | CRHBP (0.51) | CRHBPCRHR2ESR1ESR2LMNA | |
| SCHEMBL28087000 | 0.85 | CRHBP (0.51) | CRHBPCRHR2ESR1ESR2LMNA | |
| SCHEMBL9512744 | 0.85 | CRHBP (0.51) | CRHBPCRHR2ESR1ESR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113603600-A | Preparation method of 5-aminolevulinic acid hydrochloride | 山东威高药业股份有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-110218231-B | Cyclobutane dicarboxylic acid platinum complex, intermediate thereof, preparation method thereof, pharmaceutical composition and application thereof | 天津谷堆生物医药科技有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-115835909-A | Cannabinoid receptor type 2 (CB 2) modulators and uses thereof | 泰昂治疗公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-110218230-B | Vitamin C coupled platinum complex, intermediate thereof, preparation method thereof, pharmaceutical composition and application | 天津谷堆生物医药科技有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-113603600-A | Preparation method of 5-aminolevulinic acid hydrochloride | 山东威高药业股份有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-105980345-B | Method for continuously producing ketomalonic acid compound using flow reactor | 组合化学工业株式会社 | 2019-12-20 | — | — | CN | disclosed |
| CN-102395585-A | Heteroaryls and their use as pi3k inhibitors | MILLENNIUM PHARM INC | 2012-03-28 | — | — | CN | disclosed |
| CN-100360598-C | Low-dust granules of plastic additives | CIBA GEIGY AG (CH) | 2008-01-09 | — | — | CN | disclosed |
| CN-1133299-A | Method for preparation of stabilized olefines polymer | CIBA GEIGY (CH) | 1996-10-16 | — | — | CN | disclosed |
| US-5049694-A | Cardiovascular disorders | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-09-17 | — | — | US | disclosed |
| EP-0359335-A2 | Pharmaceutical composition having relaxing activity which contains a nitrate ester as active substance | CEDONA PHARMACEUTICALS B.V. (NL) | 1990-03-21 | — | — | EP | disclosed |