Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17285155 | 0.79 | ACHE (0.43) | ACHEMEN1KMT2A | |
| SCHEMBL29351118 | 0.76 | ACHE (0.42) | ACHEMEN1KMT2A | |
| SCHEMBL575759 | 0.75 | TSHR (0.48) | ACHETDP1MEN1KMT2AMMP1 | |
| SCHEMBL14966337 | 0.75 | TSHR (0.48) | ACHETDP1MEN1KMT2AMMP1 | |
| SCHEMBL575336 | 0.73 | ACHE (0.50) | ACHETDP1MEN1KMT2AMMP1 | |
| SCHEMBL575204 | 0.72 | TSHR (0.50) | ACHETDP1MEN1KMT2AMMP1 | |
| Sulfotep SCHEMBL9231339 | 0.72 | TDP1 (0.41) | ACHETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL575179 | 0.72 | TSHR (0.52) | ACHETDP1MEN1KMT2AMMP1 | |
| SCHEMBL575648 | 0.72 | ACHE (0.44) | ACHETDP1MEN1KMT2AMMP1 | |
| SCHEMBL10625218 | 0.72 | ACHE (0.44) | ACHEMEN1KMT2AMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011526-A | Combination of thiocarbamate herbicide, organophosphorus compound, antidote | ICI AMERICAS INC. (US) | 1991-04-30 | — | — | US | disclosed |
| US-4915725-A | ORGANOPHOSPHORUS COMPOUNDS PROLONG THE EFFECTIVENESS OF A SINGLE APPLICATION OF THIOCARBAMATE HERBICIDE | ICI AMERICAS, INC. (US) | 1990-04-10 | — | — | US | disclosed |