⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844029 | 0.59 | — | — | |
| SCHEMBL16732706 | 0.59 | — | — | |
| SCHEMBL5058095 | 0.59 | — | — | |
| SCHEMBL3496828 | 0.59 | — | — | |
| SCHEMBL69372 | 0.59 | — | — | |
| SCHEMBL465432 | 0.56 | — | — | |
| SCHEMBL2452467 | 0.56 | — | — | |
| SCHEMBL547356 | 0.56 | — | — | |
| SCHEMBL6202719 | 0.56 | — | — | |
| SCHEMBL21460 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055561-A | Protein conjugated with drug, dye, or label by reaction of reduced disulfide bonds with bridging compound | THE JOHNS HOPKINS UNIVERSITY (US) | 1991-10-08 | — | — | US | disclosed |
| US-4889916-A | USING A DIMERCAPTO- OR DIHALO-CONTAINING DRUG, DYE OR LABEL TO BRIDGE THE MERCAPTO GROUPS FORMED BY THE REDUCTION OF PROTEIN DISULFIDE GROUPS | THE JOHNS HOPKINS UNIVERSITY (US) | 1989-12-26 | — | — | US | disclosed |
| EP-0305967-A2 | Conjugates of interferon alpha with immunoglobulins | CIBA-GEIGY AG (CH) | 1989-03-08 | — | — | EP | disclosed |
| US-4751286-A | BRIDGING COMPOUND CONTAINING SULHYDRYL GROUPS | THE JOHNS HOPKINS UNIVERSITY (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0224120-A2 | Protein label and drug delivery system | THE JOHNS HOPKINS UNIVERSITY (US) | 1987-06-03 | — | — | EP | disclosed |