Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 5/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 8/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | BLVRB | P30043 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146813 | 1.00 | PHLPP2 (1.00) | PHLPP2POLBCYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL5146806 | 1.00 | PHLPP2 (1.00) | PHLPP2POLBCYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL8843749 | 0.86 | PHLPP2 (0.75) | PHLPP2POLBCYP2D6CYP2C9RPS6KA3 | |
| SCHEMBL8843743 | 0.86 | PHLPP2 (0.75) | PHLPP2POLBCYP2D6CYP2C9RPS6KA3 | |
| SCHEMBL10528246 | 0.83 | PHLPP2 (0.71) | PHLPP2CYP2D6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL30604557 | 0.81 | PHLPP2 (0.78) | PHLPP2POLBCYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL6250400 | 0.81 | PHLPP2 (0.78) | PHLPP2POLBCYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL14596773 | 0.81 | PHLPP2 (0.78) | PHLPP2POLBCYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL5576043 | 0.81 | PHLPP2 (0.78) | PHLPP2POLBCYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL27671132 | 0.80 | PHLPP2 (0.67) | PHLPP2CYP2D6ALDH1A1HSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055195-A | Coagulation, filtration, separation form whole blood; having two strongly polar groups separated by aromatic or heteroaroma tic rings | BOEHRINGER MANNHEIM GMBH (DE) | 1991-10-08 | — | — | US | disclosed |