Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | BRD4 | O60885 | 16/20 | 0.58 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.58 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843743 | 1.00 | PHLPP2 (0.75) | PHLPP2POLBCYP2D6BRD4RPS6KA3 | |
| SCHEMBL7813054 | 0.86 | RPS6KA3 (0.63) | PHLPP2POLBCYP2D6BRD4RPS6KA3 | |
| SCHEMBL7813050 | 0.86 | RPS6KA3 (0.63) | PHLPP2POLBCYP2D6BRD4RPS6KA3 | |
| SCHEMBL12486910 | 0.86 | PHLPP2 (0.63) | PHLPP2POLBCYP2D6BRD4RPS6KA3 | |
| SCHEMBL9875674 | 0.86 | PHLPP2 (1.00) | PHLPP2POLBCYP2D6BRD4RPS6KA3 | |
| SCHEMBL5146806 | 0.86 | PHLPP2 (1.00) | PHLPP2POLBCYP2D6BRD4RPS6KA3 | |
| SCHEMBL12486913 | 0.86 | PHLPP2 (0.63) | PHLPP2POLBCYP2D6BRD4RPS6KA3 | |
| SCHEMBL5146813 | 0.86 | PHLPP2 (1.00) | PHLPP2POLBCYP2D6BRD4RPS6KA3 | |
| SCHEMBL12486877 | 0.84 | PHLPP2 (0.60) | PHLPP2POLBCYP2D6BRD4RPS6KA3 | |
| SCHEMBL18624977 | 0.82 | POLB (0.83) | PHLPP2POLBCYP2D6RPS6KA3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618726-A | DYE HAVING LIGNIN-LIKE SUBSTITUTION PATTERN AND A MICROBE CAPABLE OF PRODUCING EXTRACELLULAR PEROXIDASE | IDAHO RESEARCH FOUNDATION, INC. (US) | 1997-04-08 | — | — | US | claimed |
| WO-1992017550-A1 | BIODEGRADABLE AZO DYES | IDAHO RESEARCH FOUNDATION, INC. (US) | 1992-10-15 | — | — | WO | claimed |
| CN-102688250-A | Synthesis and application of azo derivatives as inhibitor of RSK2 | UNIV EAST CHINA SCIENCE & TECH | 2012-09-26 | — | — | CN | disclosed |
| US-5618726-A | DYE HAVING LIGNIN-LIKE SUBSTITUTION PATTERN AND A MICROBE CAPABLE OF PRODUCING EXTRACELLULAR PEROXIDASE | IDAHO RESEARCH FOUNDATION, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| US-5486214-A | MONO OR DISAZO DYES, LIGNIN PEROXIDASE AND VERATRYL ALCOHOL MIXTURE FOR DEGRADATION OF DYES | IDAHO RESEARCH FOUNDATION, INC. (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1992017550-A1 | BIODEGRADABLE AZO DYES | IDAHO RESEARCH FOUNDATION, INC. (US) | 1992-10-15 | — | — | WO | disclosed |