SCHEMBL9875696

SCHEMBL9875696

OC1CCCc2nc3cc(Cl)ccc3c(NCc3ccc(F)cc3)c21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9874134 0.90 ACHE (0.67) ACHE
SCHEMBL9874502 0.86
SCHEMBL9876171 0.85
SCHEMBL9875894 0.83
SCHEMBL10848116 0.82
SCHEMBL10847412 0.80
SCHEMBL10847762 0.80
SCHEMBL9875739 0.79
SCHEMBL10847375 0.79
SCHEMBL9874509 0.78 ACHE (0.67) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4695573-A COGNITION ACTIVATORS HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1987-09-22 US claimed
EP-2681554-B1 BLOOD COLLECTION DEVICE CONTAINING LYSOPHOSPHOLIPASE INHIBITOR BECTON DICKINSON CO (US) 2017-08-09 EP disclosed
US-9459187-B2 Blood collection device containing lysophospholipase inhibitor BECTON, DICKINSON AND COMPANY (US) 2016-10-04 US disclosed
CN-104244902-A Sample collection devices with blood stabilizing agents BECTON DICKINSON CO 2014-12-24 CN disclosed
US-20140030754-A1 BLOOD COLLECTION DEVICE CONTAINING LYSOPHOSPHOLIPASE INHIBITOR BECTON, DICKINSON AND COMPANY (US) 2014-01-30 US disclosed
CN-203203992-U Blood collection device containing lysophospholipase inhibitor BECTON DICKINSON CO 2013-09-18 CN disclosed
US-20130209985-A1 SAMPLE COLLECTION DEVICES WITH BLOOD STABILIZING AGENTS BECTON, DICKINSON AND COMPANY 2013-08-15 US disclosed
WO-2012121998-A1 BLOOD COLLECTION DEVICE CONTAINING LYSOPHOSPHOLIPASE INHIBITOR BECTON, DICKINSON AND COMPANY (US) 2012-09-13 WO disclosed
EP-0179383-B1 9-AMINO-1,2,3,4-TETRAHYDROACRIDIN-1-OL AND RELATED COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-05-29 EP disclosed
US-4839364-A ALZHEIMER*S DISEASE; CHOLINESTERASE INHIBITORS HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1989-06-13 US disclosed
US-4835275-A Method of preparing 9-amino-1,2,3,4,-tetrahydroacridin-1-ones and related compounds HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1989-05-30 US disclosed
US-4754050-A COGNITION ACTIVATORS HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1988-06-28 US disclosed
US-4695573-A COGNITION ACTIVATORS HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1987-09-22 US disclosed