Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874182 | 0.87 | MEN1 (0.41) | KMT2AMEN1NPC1TNKS2ALDH1A1 | |
| SCHEMBL13834469 | 0.78 | KMT2A (0.68) | KMT2AMEN1NPC1TNKS2ALDH1A1 | |
| SCHEMBL11502286 | 0.76 | ALDH1A1 (0.48) | KMT2AMEN1NPC1TNKS2ALDH1A1 | |
| SCHEMBL18314788 | 0.76 | KMT2A (0.59) | KMT2AMEN1NPC1TNKS2ALDH1A1 | |
| SCHEMBL6259561 | 0.76 | TNKS2 (0.57) | KMT2AMEN1NPC1TNKS2ALDH1A1 | |
| SCHEMBL22889194 | 0.74 | KMT2A (0.47) | KMT2AMEN1NPC1TNKS2ALDH1A1 | |
| SCHEMBL18125709 | 0.73 | CYP2C19 (0.45) | KMT2AMEN1NPC1TNKS2ALDH1A1 | |
| SCHEMBL11812669 | 0.73 | CYP2C19 (0.45) | KMT2AMEN1NPC1TNKS2ALDH1A1 | |
| SCHEMBL15604879 | 0.73 | — | — | |
| SCHEMBL1316915 | 0.73 | MEN1 (0.44) | KMT2AMEN1NPC1TNKS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175648-B1 | Heat-hardenable compositions containing a polymaleinimide and a bicyclo[2.2.1]heptene-5-2,3-dicarboximide, and their use | CIBA-GEIGY AG (CH) | 1991-05-22 | — | — | EP | disclosed |
| EP-0272210-A2 | (Poly)oxaalkylene-alpha-, omega-bisimides of allyl-bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acids, and their use | CIBA-GEIGY AG (CH) | 1988-06-22 | — | — | EP | disclosed |
| US-4745166-A | Heat-curable mixture containing substituted bicyclo (2.2.1) hept-5-ene-2,3-dicarboximide and polymaleimide, and ethylenically unsaturated phenolic compound | CIBA-GEIGY CORPORATION (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0175648-A2 | Heat-hardenable compositions containing a polymaleinimide and a bicyclo[2.2.1]heptene-5-2,3-dicarboximide, and their use | CIBA-GEIGY AG (CH) | 1986-03-26 | — | — | EP | disclosed |
| US-4131707-A | POLYMALEIMIDES | CIBA-GEIGY CORPORATION (US) | 1978-12-26 | — | — | US | disclosed |
| US-3950279-A | DI- OR TRI-MALEIMIDE, AZOMETHINE, SOLID FOAMING AGENT | CIBA-GEIGY CORPORATION (US) | 1976-04-13 | — | — | US | disclosed |
| US-3947385-A | Mixtures containing prepolymers, which can be converted to heat-resistant foamed plastics | CIBA-GEIGY CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |