SCHEMBL9875977

SCHEMBL9875977

C/C=C\c1cccc(O)c1/C=C\C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IAPP P10997 4/20 0.40
TTR P02766 1/20 0.39
ERN1 O75460 1/20 0.39
LMNA P02545 3/20 0.38
MAPT P10636 2/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
TRPA1 O75762 2/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
RAB9A P51151 1/20 0.38
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
TRIM24 O15164 1/20 0.37
TRIM33 Q9UPN9 1/20 0.37
NFKB1 P19838 2/20 0.36
CDK4 P11802 1/20 0.36
CCND1 P24385 1/20 0.36
JUN P05412 1/20 0.36
NFE2L2 Q16236 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9281951 1.00 IAPP (0.40) IAPPTTRERN1LMNAMAPT
SCHEMBL9742937 0.86 TTR (0.50) IAPPTTRERN1LMNAMAPT
SCHEMBL9742941 0.86 TTR (0.50) IAPPTTRERN1LMNAMAPT
SCHEMBL4745105 0.86 IAPP (0.38) IAPPTTRERN1LMNAMAPT
SCHEMBL21841052 0.86 IAPP (0.37) IAPPTTRERN1LMNAMAPT
SCHEMBL12992626 0.86 IAPP (0.37) IAPPTTRERN1LMNAMAPT
SCHEMBL3842854 0.84 ELANE (0.36) LMNAESR1ESR2NFE2L2ALDH1A1
SCHEMBL3842857 0.84 ELANE (0.36) LMNAESR1ESR2NFE2L2ALDH1A1
SCHEMBL28900446 0.82 CDK4 (0.41) IAPPTTRERN1LMNAMAPT
SCHEMBL9251009 0.80 IAPP (0.60) IAPPERN1LMNAMAPTTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140249272-A1 EMULSION POLYMERIZATION METHOD USING REACTIVE EMULSIFIER, AQUEOUS POLYMER DISPERSION OBTAINED BY THE SAME, AND POLYMER FILM Dai-ich Kpgyo Seiyaku Co., Ltd. (JP) 2014-09-04 US disclosed
EP-2765142-A1 EMULSION POLYMERIZATION METHOD USING REACTIVE EMULSIFYING AGENT, AQUEOUS POLYMER DISPERSION OBTAINED BY SAME, AND POLYMER FILM Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2014-08-13 EP disclosed
US-5023310-A Chain extended epoxy resin BASF AKTIENGESELLSCHAFT 1991-06-11 US disclosed
US-4923928-A High impact strength, adhesives, prepregs, composites BASF AKTIENGESELLSCHAFT (DE) 1990-05-08 US disclosed
US-4902778-A Propenylphenoxy-terminated oligomeric tougheners and their use in toughening thermosetting bismaleimide resin compositions BASF AKTIENGESELLSCHAFT (DE) 1990-02-20 US disclosed