Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.60 |
| ▸ | ERN1 | O75460 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251021 | 1.00 | IAPP (0.60) | IAPPERN1POLBGAARAB9A | |
| SCHEMBL9745412 | 1.00 | IAPP (0.60) | IAPPERN1POLBGAARAB9A | |
| SCHEMBL2047855 | 0.88 | IAPP (0.45) | IAPPERN1POLBGAARAB9A | |
| SCHEMBL2047852 | 0.88 | IAPP (0.45) | IAPPERN1POLBGAARAB9A | |
| SCHEMBL8894545 | 0.88 | IAPP (0.45) | IAPPERN1POLBGAARAB9A | |
| SCHEMBL308223 | 0.85 | ERN1 (0.65) | IAPPERN1POLBGAARAB9A | |
| SCHEMBL6338287 | 0.85 | IAPP (0.55) | IAPPERN1POLBGAARAB9A | |
| SCHEMBL6338290 | 0.85 | IAPP (0.55) | IAPPERN1POLBGAARAB9A | |
| Pyrogallol SCHEMBL23319311 | 0.83 | ALDH1A1 (0.71) | IAPPERN1POLBGAARAB9A | |
| Pyrogallol SCHEMBL23319312 | 0.83 | ALDH1A1 (0.71) | IAPPERN1POLBGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435418-B1 | A dispersant/antioxidant viscosity index improving lubricant additive | TEXACO DEVELOPMENT CORP (US) | 1995-01-04 | — | — | EP | claimed |
| US-11746364-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-09-05 | — | — | US | disclosed |
| US-11739354-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-08-29 | — | — | US | disclosed |
| US-20160243137-A1 | Anti-Inflammatory Compounds and Use Thereof | MEDICON PHARMACEUTICALS, INC. | 2016-08-25 | — | — | US | disclosed |
| US-9408822-B2 | Compositions for prevention/prophylactic treatment of poison ivy dermatitis | THE UNIVERSITY OF MISSISSIPPI (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150202176-A1 | Compositions for Prevention/Prophylactic Treatment of Poison Ivy Dermatitis | THE UNIVERSITY OF MISSISSIPPI | 2015-07-23 | — | — | US | disclosed |
| US-20120316139-A1 | ANTI-INFLAMMATORY COMPOUNDS AND USES THEREOF | MEDICON PHARMACEUTICALS, INC. | 2012-12-13 | — | — | US | disclosed |
| US-20120316139-A1 | ANTI-INFLAMMATORY COMPOUNDS AND USES THEREOF | MEDICON PHARMACEUTICALS, INC. | 2012-12-13 | — | — | US | disclosed |
| US-8236820-B2 | Anti-inflammatory compounds and uses thereof | MEDICON PHARMACEUTICALS, INC. | 2012-08-07 | — | — | US | disclosed |
| US-8236820-B2 | Anti-inflammatory compounds and uses thereof | MEDICON PHARMACEUTICALS, INC. | 2012-08-07 | — | — | US | disclosed |
| US-7585997-B2 | Compounds and compositions for treating dysproliferative diseases, and methods of use thereof | CHESTERFORD ENTERPRISES LIMITED (KY) | 2009-09-08 | — | — | US | disclosed |
| US-20090099137-A1 | Anti-Inflammatory Compounds and Uses Thereof | MEDICON PHARMACEUTICALS, INC. | 2009-04-16 | — | — | US | disclosed |
| US-20090099137-A1 | Anti-Inflammatory Compounds and Uses Thereof | MEDICON PHARMACEUTICALS, INC. | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099137-A1 | Anti-Inflammatory Compounds and Uses Thereof | TNF, NFKBIA, IL6 | IAPP 158/4885ERN1 2989/4885POLB 2116/4885 |
| US-20120316139-A1 | ANTI-INFLAMMATORY COMPOUNDS AND USES THEREOF | NFKBIA, TNF, MPO | IAPP 203/4885ERN1 3710/4885POLB 2134/4885 |
| US-20150202176-A1 | Compositions for Prevention/Prophylactic Treatment of Poison Ivy Dermatitis | UGT1A3, IL33, ITCH | IAPP 2807/4885ERN1 4094/4885POLB 1475/4885 |
| US-20160243137-A1 | Anti-Inflammatory Compounds and Use Thereof | NFKBIA, TNF, RELA | IAPP 198/4885ERN1 3856/4885POLB 2106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.