Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875842 | 0.83 | G6PD (0.47) | G6PDCASP7CASP6HMGB1FOLH1 | |
| SCHEMBL17433852 | 0.82 | CLCN2 (0.50) | G6PDCASP7CASP6HMGB1FOLH1 | |
| SCHEMBL21723958 | 0.82 | G6PD (0.46) | G6PDCASP7CASP6HMGB1FOLH1 | |
| SCHEMBL5135887 | 0.81 | G6PD (0.56) | G6PDCASP7CASP6HMGB1FOLH1 | |
| SCHEMBL808482 | 0.79 | G6PD (0.57) | G6PDCASP7CASP6HMGB1FOLH1 | |
| SCHEMBL30762619 | 0.79 | G6PD (0.57) | G6PDCASP7CASP6HMGB1FOLH1 | |
| SCHEMBL7157314 | 0.79 | G6PD (0.53) | G6PDCASP7CASP6HMGB1ALOX15 | |
| SCHEMBL7720169 | 0.78 | G6PD (0.56) | G6PDCASP7CASP6HMGB1FOLH1 | |
| SCHEMBL6832900 | 0.78 | G6PD (0.56) | G6PDCASP7CASP6HMGB1FOLH1 | |
| SCHEMBL27902532 | 0.78 | G6PD (0.55) | G6PDCASP7CASP6HMGB1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408546-A1 | IMPROVEMENTS RELATING TO DRUG DELIVERY SYSTEMS. | CANCER RES CAMPAIGN TECH (GB) | 1991-01-23 | — | — | EP | claimed |
| WO-1988007378-A1 | IMPROVEMENTS RELATING TO DRUG DELIVERY SYSTEMS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LTD. (GB) | 1988-10-06 | — | — | WO | claimed |