SCHEMBL9876058

SCHEMBL9876058

CN(C)S(=O)(=O)n1cc(-c2ccc(Cl)c(C=NO)c2Cl)nc1C=NO

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
ESR1 P03372 1/20 0.32
CA9 Q16790 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9876056 0.85
SCHEMBL9876172 0.84 LMNA (0.39)
SCHEMBL9875494 0.81
SCHEMBL9876574 0.78 MAPT (0.33)
SCHEMBL9876372 0.77 TSHR (0.43)
SCHEMBL9876370 0.77 TSHR (0.43)
SCHEMBL9875847 0.74
SCHEMBL9875843 0.74
SCHEMBL9876158 0.70 LMNA (0.42)
SCHEMBL9875613 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5045557-A Imidazable fungicides and use thereof SCHERING AGROCHEMICALS LTD. (GB) 1991-09-03 US disclosed
EP-0284277-A1 Cyanoimidazole fungicides AgrEvo UK Limited (GB) 1988-09-28 EP disclosed