Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876095 | 1.00 | BLM (0.49) | BLMMCOLN3LMNACHRM2CHRM4 | |
| SCHEMBL9504121 | 0.84 | CHRNB2 (0.50) | BLMMCOLN3LMNACHRM2CHRM4 | |
| SCHEMBL9504116 | 0.84 | CHRNB2 (0.50) | BLMMCOLN3LMNACHRM2CHRM4 | |
| SCHEMBL10564077 | 0.77 | CHRNB2 (0.60) | BLMMCOLN3LMNACHRM2CHRM4 | |
| SCHEMBL10564080 | 0.77 | CHRNB2 (0.60) | BLMMCOLN3LMNACHRM2CHRM4 | |
| SCHEMBL10566185 | 0.76 | CHRNB2 (0.44) | BLMMCOLN3LMNACHRM2CHRM4 | |
| SCHEMBL9506150 | 0.76 | CHRM2 (0.50) | BLMMCOLN3LMNACHRM2CHRM4 | |
| SCHEMBL9506147 | 0.76 | CHRM2 (0.50) | BLMMCOLN3LMNACHRM2CHRM4 | |
| SCHEMBL10566192 | 0.76 | CHRNB2 (0.44) | BLMMCOLN3LMNACHRM2CHRM4 | |
| SCHEMBL9503691 | 0.75 | CHRNB2 (0.43) | BLMMCOLN3LMNACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073561-A | N-substituted-pyridinyl oximes | WARNER-LAMBERT COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| US-4929734-A | ANTIINFLAMMATORY AGENTS, ANTIDEPRESSANTS | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| US-4798841-A | COGNITION ACTIVATORS, ANALGESICS | WARNER-LAMBERT COMPANY (US) | 1989-01-17 | — | — | US | disclosed |
| EP-0291673-A1 | Tetrahydropyridine oximes, a process for their preparation and use thereof as cholinergic agents | WARNER-LAMBERT COMPANY (US) | 1988-11-23 | — | — | EP | disclosed |
| US-4710508-A | ANALGESICS | WARNER-LAMBERT COMPANY (US) | 1987-12-01 | — | — | US | disclosed |