Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 10/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.54 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.51 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.51 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876121 | 1.00 | ABCC9 (0.56) | ABCC9ABCB1ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9876116 | 1.00 | ABCC9 (0.56) | ABCC9ABCB1ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9876217 | 0.88 | ABCC9 (0.57) | ABCC9ABCB1 | |
| SCHEMBL9876793 | 0.88 | ABCC9 (0.56) | ABCC9ABCB1ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9876783 | 0.88 | ABCC9 (0.56) | ABCC9ABCB1ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9876788 | 0.88 | ABCC9 (0.56) | ABCC9ABCB1ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9876225 | 0.88 | ABCC9 (0.57) | ABCC9ABCB1 | |
| SCHEMBL9876219 | 0.88 | ABCC9 (0.57) | ABCC9ABCB1 | |
| SCHEMBL9875810 | 0.86 | ABCC9 (0.54) | ABCC9ABCB1ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9876352 | 0.86 | ABCB1 (0.55) | ABCC9ABCB1ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071871-A | Pharmaceutically useful benzo(β)pyranes and pyranopyridines | SANDOZ LTD. (CH) | 1991-12-10 | — | — | US | disclosed |