Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876131 | 1.00 | GRM2 (0.54) | GRM2NPC1RAB9ASMN1; SMN2MGLL | |
| SCHEMBL9358344 | 0.86 | TP53 (0.44) | THRATHRBTSHRALDH1A1MAPT | |
| SCHEMBL9874737 | 0.86 | TP53 (0.44) | THRATHRBTSHRALDH1A1MAPT | |
| SCHEMBL9874731 | 0.86 | TP53 (0.44) | THRATHRBTSHRALDH1A1MAPT | |
| SCHEMBL5684559 | 0.86 | TP53 (0.44) | THRATHRBTSHRALDH1A1MAPT | |
| SCHEMBL8746436 | 0.86 | TP53 (0.44) | THRATHRBTSHRALDH1A1MAPT | |
| SCHEMBL9631107 | 0.85 | THRA (0.42) | GRM2NPC1RAB9ASMN1; SMN2THRA | |
| SCHEMBL9358359 | 0.84 | RARB (0.42) | THRATHRBTSHRALDH1A1MAPT | |
| SCHEMBL8746433 | 0.84 | RARB (0.42) | THRATHRBTSHRALDH1A1MAPT | |
| SCHEMBL10588481 | 0.83 | KMT2A (0.40) | GRM2NPC1RAB9ASMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053507-A | Liquid crystal dopants | ARAKAWA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-10-01 | — | — | US | disclosed |