Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876177 | 1.00 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9876183 | 1.00 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9874277 | 0.85 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL6369151 | 0.85 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL31060528 | 0.85 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9874273 | 0.85 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL8137096 | 0.82 | ABCC9 (0.39) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL8137100 | 0.82 | ABCC9 (0.39) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9875883 | 0.82 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9875873 | 0.82 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071871-A | Pharmaceutically useful benzo(β)pyranes and pyranopyridines | SANDOZ LTD. (CH) | 1991-12-10 | — | — | US | disclosed |