Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876260 | 1.00 | GAA (0.38) | GAAMAPTPOLBSMN1; SMN2LMNA | |
| SCHEMBL9876314 | 0.80 | MAPK1 (0.36) | GAAMAPTPOLBSMN1; SMN2LMNA | |
| SCHEMBL9876312 | 0.80 | MAPK1 (0.36) | GAAMAPTPOLBSMN1; SMN2LMNA | |
| SCHEMBL9876221 | 0.72 | GAA (0.60) | GAAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9876224 | 0.72 | GAA (0.60) | GAAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29364216 | 0.72 | SMN1; SMN2 (0.39) | MAPTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL287450 | 0.72 | KDM4E (0.47) | MAPTALDH1A1KDM4EPKMKMT2A | |
| SCHEMBL335305 | 0.72 | SMN1; SMN2 (0.39) | MAPTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29526925 | 0.72 | KDM4E (0.47) | MAPTALDH1A1KDM4EPKMKMT2A | |
| Hydrochloric Acid SCHEMBL5755935 | 0.70 | KDM4E (0.46) | MAPTALDH1A1KDM4EPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049561-A | Anthelmintic acylhydrazones, method of use and compositions | THE UPJOHN COMPANY (US) | 1991-09-17 | — | — | US | claimed |
| EP-0370065-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1990-05-30 | — | — | EP | claimed |
| WO-1989000992-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1989-02-09 | — | — | WO | claimed |