Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874806 | 0.97 | REN (0.47) | REN | |
| SCHEMBL10630739 | 0.95 | REN (0.45) | REN | |
| SCHEMBL9876291 | 0.94 | REN (0.47) | REN | |
| SCHEMBL10459449 | 0.94 | REN (0.44) | REN | |
| SCHEMBL9876392 | 0.93 | REN (0.43) | REN | |
| SCHEMBL9876262 | 0.92 | REN (0.45) | REN | |
| SCHEMBL9876377 | 0.92 | REN (0.43) | REN | |
| SCHEMBL9876598 | 0.88 | REN (0.52) | REN | |
| SCHEMBL9876341 | 0.87 | REN (0.54) | REN | |
| SCHEMBL9876329 | 0.84 | REN (0.46) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992562-A | Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues | PFIZER INC. (US) | 1991-02-12 | — | — | US | disclosed |
| US-4948913-A | Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues | PFIZER INC. (US) | 1990-08-14 | — | — | US | disclosed |
| US-4729985-A | Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues | PFIZER INC. (US) | 1988-03-08 | — | — | US | disclosed |