Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | ATM | Q13315 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394504 | 0.88 | HDAC3 (0.55) | KDM4EATMHTTHTR2AHDAC3 | |
| Hydrochloric Acid SCHEMBL3491998 | 0.86 | HDAC3 (0.54) | KDM4EATMHTTHTR2AHDAC3 | |
| SCHEMBL730875 | 0.82 | HTR2A (0.57) | KDM4EATMHTTHTR2AALDH1A1 | |
| SCHEMBL13791452 | 0.79 | HTR2A (0.49) | KDM4EATMHTTHTR2AHDAC3 | |
| SCHEMBL7269382 | 0.78 | MAPT (0.61) | KDM4EATMHTTHTR2AALDH1A1 | |
| SCHEMBL4351287 | 0.78 | KDM4E (0.69) | KDM4EATMHTTALDH1A1HPGD | |
| SCHEMBL6560495 | 0.78 | KDM4E (0.69) | KDM4EATMHTTHTR2AALDH1A1 | |
| SCHEMBL9444261 | 0.78 | KDM4E (0.69) | KDM4EATMHTTALDH1A1HPGD | |
| SCHEMBL1821870 | 0.78 | KDM4E (0.69) | KDM4EATMHTTALDH1A1HPGD | |
| SCHEMBL1828856 | 0.78 | KDM4E (0.69) | KDM4EATMHTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071871-A | Pharmaceutically useful benzo(β)pyranes and pyranopyridines | SANDOZ LTD. (CH) | 1991-12-10 | — | — | US | disclosed |