SCHEMBL9876485

SCHEMBL9876485

CCCCCCCCCCCCCCCCNS(=O)(=O)c1c(C)ccc(-n2oc(C(C)(C)C)c(COc3ccc(NC(C)=O)cc3)c2=O)c1[N+](=O)[O-]

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ATM Q13315 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MAPT P10636 3/20 0.33
ALDH1A1 P00352 5/20 0.33
GHSR Q92847 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
POLB P06746 1/20 0.32
TBXA2R P21731 3/20 0.32
NPY1R P25929 1/20 0.32
NPY2R P49146 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9876665 0.90 NCOA1 (0.31) LMNASMN1; SMN2NPSR1ALDH1A1TBXA2R
SCHEMBL9876455 0.83 HTT (0.32) LMNASMN1; SMN2MAPTALDH1A1POLB
SCHEMBL9876854 0.83 HTT (0.32) LMNASMN1; SMN2MAPTALDH1A1POLB
SCHEMBL9876597 0.80 MAPT (0.34) LMNASMN1; SMN2NPSR1MAPTALDH1A1
SCHEMBL9771372 0.73 MAPT (0.34) LMNASMN1; SMN2MAPTALDH1A1POLB
SCHEMBL9876484 0.73 MAPT (0.34) LMNASMN1; SMN2MAPTALDH1A1POLB
SCHEMBL9877541 0.70 ALDH1A1 (0.38) LMNASMN1; SMN2MAPTALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL9864700 0.70 ALDH1A1 (0.48) LMNASMN1; SMN2MAPTALDH1A1L3MBTL1
SCHEMBL9775630 0.63 POLB (0.75) LMNASMN1; SMN2NPSR1MAPTALDH1A1
SCHEMBL4066416 0.62 POLB (0.77) LMNASMN1; SMN2NPSR1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5049477-A Image forming, etching, plating FUJI PHOTO FILM CO., LTD. (JP) 1991-09-17 US disclosed