Menadione

Menadione

SCHEMBL987664

CC1=CC(=O)c2ccccc2C1=O.[NaH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.95
ALDH1A1 P00352 5/20 0.95
MEN1 O00255 5/20 0.95
KMT2A Q03164 5/20 0.95
MAPK1 P28482 5/20 0.95
LMNA P02545 5/20 0.95
CDC25B P30305 4/20 0.95
SMN1; SMN2 Q16637 4/20 0.95
IDO1 P14902 3/20 0.95
CDC25A P30304 3/20 0.95
HPGD P15428 3/20 0.95
BLM P54132 3/20 0.95
TP53 P04637 2/20 0.95
CYP1A2 P05177 2/20 0.95
CYP3A4 P08684 2/20 0.95
HSPD1 P10809 2/20 0.95
HSPE1 P61604 2/20 0.95
TST Q16762 2/20 0.95
GAA P10253 2/20 0.95
ATM Q13315 2/20 0.95

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Menadione SCHEMBL19356853 0.98 MAPT (1.00) MAPTALDH1A1MEN1KMT2AMAPK1
Menadione SCHEMBL29351164 0.98 MAPT (1.00) MAPTALDH1A1MEN1KMT2AMAPK1
Menadione SCHEMBL25970 0.98 MAPT (1.00) MAPTALDH1A1MEN1KMT2AMAPK1
Menadione SCHEMBL1364028 0.98 MAPT (1.00) MAPTALDH1A1MEN1KMT2AMAPK1
Menadione SCHEMBL9163371 0.95 MAPT (0.95) MAPTALDH1A1MEN1KMT2AMAPK1
Menadione SCHEMBL9807661 0.95 MAPT (0.95) MAPTALDH1A1MEN1KMT2AMAPK1
Menadione SCHEMBL6680739 0.95 MAPT (0.95) MAPTALDH1A1MEN1KMT2AMAPK1
Menadione SCHEMBL3411128 0.95 MAPT (0.95) MAPTALDH1A1MEN1KMT2AMAPK1
Menadione SCHEMBL9812440 0.95 MAPT (0.95) MAPTALDH1A1MEN1KMT2AMAPK1
Menadione SCHEMBL28388399 0.95 MAPT (0.95) MAPTALDH1A1MEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1601256-B1 DIETARY SUPPLEMENT FOR ATHLETIC PETS NESTEC SA (CH) 2014-06-25 EP claimed
US-5116406-A Choline chloride and vitamin k MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-05-26 US claimed
EP-0275880-B1 PROCESS FOR PRODUCING STABILIZED MENADION BISULFIDE FORMULATIONS BASF Aktiengesellschaft (DE) 1991-07-24 EP claimed
JP-4046103-A None JP disclosed
JP-6237700-A None JP disclosed
US-20240075077-A1 Bacillus Strains Improving Health and Performance of Production Animals NOVOZYMES A/S (DK) 2024-03-07 US disclosed
US-11801272-B2 Bacillus strains improving health and performance of production animals NOVOZYMES A/S (DK) 2023-10-31 US disclosed
EP-4070666-A1 ENZYME-RICH EXTRACT AND USE THEREOF IN PRE-TREATMENT OF PLANT FEEDSTUFF-BASED DIETS CIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental (PT) 2022-10-12 EP disclosed
US-20220143110-A1 Bacillus Strains Improving Health and Performance of Production Animals NOVOZYMES A/S (DK) 2022-05-12 US disclosed
US-11166989-B2 Bacillus strains improving health and performance of production animals NOVOZYMES A/S (DK) 2021-11-09 US disclosed
US-11041145-B2 Cell culture PHILIP MORRIS PRODUCTS S.A. (CH) 2021-06-22 US disclosed
EP-0692252-A1 Composition containing inulin or oligofructose for use in cancer treatment "Raffinerie Tirlemontoise", société anonyme: (BE) 1996-01-17 EP disclosed
EP-0430164-B1 Process for preparation of 2-substituted-1,4-naphthoquinone NIPPON CATALYTIC CHEM IND (JP) 1995-03-22 EP disclosed
JP-H06237700-A VITAMIN K3 PREPARATION FOR ADDITION TO FEED NIPPON NOUSAN KOGYO KK 1994-08-30 JP disclosed
US-5329026-A Oxidation of substituted naphthoquinone, adding a diene compound to reaction product, separation NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1994-07-12 US disclosed
US-5116406-A Choline chloride and vitamin k MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-05-26 US disclosed
JP-H0446103-A GROWTH ACTIVATING AGENT OF CROP FOR AGRICULTURE AND HORTICULTURE AND METHOD FOR REDUCING PHYTOTOXICITY BY HERBICIDE TOMOE KAGAKU KOGYO KK 1992-02-17 JP disclosed
EP-0430164-A2 Process for preparation of 2-substituted-1,4-naphthoquinone NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) 1991-06-05 EP disclosed
EP-0234940-B1 NOVEL DERIVATIVES BASED UPON PYRIDO-MENADIONE ADDUCTS AND USES THEREOF Heterochemical Corporation (US) 1991-04-17 EP disclosed
EP-0234940-A2 Novel derivatives based upon pyrido-menadione adducts and uses thereof Heterochemical Corporation (US) 1987-09-02 EP disclosed